Two drivers were under the influence of alcohol, including one driving on a suspended license, according to WJZ.
Another person was reportedly arrested for driving on a revoked license.
More than 1,000 vehicles passed through the checkpoint between Friday night and Saturday morning in Savage, according to Fox 45.
Funded in part by a grant from the Maryland Highway Safety Office, the sobriety checkpoint initiative is designed to raise awareness about impaired driving while reducing the number of drunk drivers on the roads, according to police.
Approximately 27 percent of fatal collisions in Howard County in 2013 were alcohol related, police said.